mavorixafor will increase the degree or impact of codeine by impacting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a solid CYP2D6 inhibitor) is contraindicated with medicine which are hugely depending on CYP2D6 for clearance.Critical Allergic Reactions. Dextromethorphan could trigger allergic reactions, which may be serious. Qu